Among the various chemical molecules, Quinone is one of the most important groups, including Naphthaquinone, Anthraquinone, and Benzoquinone. Thymoquinone is from the same group as Benzoquinone, which has pharmacological properties and therapeutic potential.
Thymoquinone: It is a phytochemical compound found in many plant extracts, including Nigella sativa Cinderus (male frankincense), horse mint, coniferous plants, including cypress, and plants of the star family, including sunflowers and chrysanthemums. .
Thymoquinone has a therapeutic effect as an immunostimulant, antioxidant, anti-inflammatory, anti-tumor, anti-microbial and anti-carcinogenic.
Thymoquinone acts as an antimicrobial through various mechanisms, including inhibiting the biofilm formation of bacterial cells (the most important virulence factors), up to 90% inhibition of the biofilm formation of Staphylococcus aureus, Pseudomonas Argonosa, Escherichia coli and Salmonella typhimre, as well as inhibiting the oxidative activity of bacterial cells while reducing the number of bacterial cells.
In addition to blocking the effectiveness of the efflux pump protein.